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KMID : 0378019720150110097
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New Medical Journal
1972 Volume.15 No. 11 p.97 ~ p.114
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The Experimental Studies on the Changes in the White Cell Count Following tooth Extraction
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Abstract
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The purpose of my work was to investigate to what extent tooth extraction influences the what blood cell count.
Tooth extraction has an immediate effect upon the blood cell count of rabbits under local anesthesia. The dental patients have various physiological reaction in order to adjustment to be obtained stress due to dental managements.
The author had studied the effects of tooth extraction under local anesthesia, such as items, changing the body weight, erythrocytes number, leukocytes number and differential count in pre-and postoperation period.
Materials and Method
The experimental materials being used in this study were 24 white male rabbits having body weight ranging 1300-1750 gram and about 3 months aged. They were considered the most suitable small laboratory animals, because their dental development and morphology is well established.
All experimental rabbits had being extracted their anterior upper and lower teeth on left and right under local anesthesia with 2 % Lidocanine Hcl (1:50.000 with epinephrine).
In each experimental rabbit, body weight, erythrocyte, leukocyte and differential count in preoperation, 2 weeks and one week before, and in postoperation, one hour, 2 hours, 3 hours, 4 hours, 12 hours, 18 hours, 24 hours, 38 hours, 2nd day, 3rd day, ... 6 th day, 8 th day, 10 th day and 12 th day after were measured.
Summary and Conclusion
The results were as follow:
1. The body weight was not remarkably for preoperation, two weeks before, but not increased at all for postoperation, one week after.
2. Erythrocyte counts were decreased remarkably at 60 minutes to first day after surgery in experimental rabbits, but recovered normally on 6th day after extraction.
3. Leukocyte count were increased remarkably at 2 hours after surgery.
4. Neutrophil levels in postoperation were increased at 60 minutes after surgery and gradually similar to the levels of preoperative state.
Lymphocyte levels in postoperation were decreased at 60 minutes after surgery and gradually similar to the levels of preoperative state.
Eosinophil levels in postoperation were decreased at 2 hours after surgery and gradually similar to the level of preopertive state.
Basophil and Moncyte levels in postoperation were not remarkably change for postoperation.
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